bs-82345C
[Life Science]
Fasnall HCl
DATASHEET
Formulation Beige solid
Storage: -20°C
Product Information:
Potent and selective fatty acid synthase (FASN) inhibitor acting via interfering with cofactor binding.1 IC50s = 147 and 213 nM respectively for inhibition of acetate and glucose incorporation into total lipids in HepG2 cells. IC50=5.84 μM in an isolated enzyme assay. Displays potent antitumor activity in the MMTV-Neu HER2+ breast cancer model.1 Reduces HIV-1 virion production by 90% (EC50=213 nM).2
Description:
CAS Number: 929978-58-5<br></br>Chemical Name: 5,6-Dimethyl-N-[1-(phenylmethyl)-3-pyrrolidinyl]thieno[2,3-d]pyrimidin-4-amine benzenesulfonate hydrochloride<br></br>Molecular weight: 374.93<br></br>Formula: C19H22N4S • HCl<br></br>Solubility: DMSO (up to 25 mg/ml) or in Water (up to 45 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.