DATASHEET
Formulation
Orange solid
Storage:
-20°C
Product Information:
Acts as an artificial co-chaperone for HSP701. The activity of compound 115-7c mirrors those of HSP40 stimulating the ATPase and protein-folding activities of prokaryotic HSP70. Increases tau levels in cell lines overexpressing tau2. Induces solubilization of polyglutamine and exacerbates polyQ-mediated toxicity3,4. An important probe for understanding HSP70 functions4
Description:
CAS Number: 908074-72-6<br></br>Chemical Name: 4-(5-((Benzyloxycarbonyl)-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)butanoic acid<br></br>Molecular weight: 477.34<br></br>Formula: C23H22Cl2N2O5<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC NMR (Conforms)