bs-82322C
[Life Science]
Ro 31-8425 HCl
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
Selective, reversible, ATP-competitive inhibitor of protein kinase C. Inhibits PKCα, β1, β2, γ and ε, IC50= 8, 8, 14,13 and 39 nM respectively.1 Extremely useful tool for probing PKC-dependent physiology2 or signaling pathways3. Increases MSC adhesion to an ICAM-1 coated substrate in vitro and enables targeted delivery of systematically administered MSCs to inflamed sites in vivo in a CD11a-dependent manner.4 Cell permeable.
Description:
CAS Number: 145317-11-9<br></br>Chemical Name: 3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrol-2,5-dione hydrochloride<br></br>Molecular weight: 460.96<br></br>Formula: C26H24N4O2 · HCl<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Red solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 1 mg, 5 mg 5 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.