DATASHEET
Formulation
Pale yellow solid
Storage:
-20°C
Product Information:
DiMNF is a selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). It exhibits antiinflammatory activity including suppression of cytokine-mediated acute phase genes through dissociation of non-dioxin-response element (DRE) AHR activity from DRE-dependent xenobiotic gene expression1. Represses the cytokine-mediated induction of CD55 and therefore may have therapeutic potential in regulating the immune response to tumor formation2. Represses estrogen-inducible transcription3.
Description:
CAS Number: 14756-24-2<br></br>Chemical Name: 2-(3,2-Dimethoxyphenyl)-4H-naphtho[1,2-b]pyran-4-one<br></br>Molecular weight: 332.45<br></br>Formula: C21H16O4<br></br>Solubility: DMSO (1.5 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 99% by HPLC NMR (Conforms)