DATASHEET
Formulation
Orange solid
Storage:
RT
Product Information:
Aquaporin 4 channel blocker, IC50 = 3.1 μM.1 Reduces ischemic cerebral edema in a mouse model of focal cerebral ischemia using MRI.2 Increases regional cerebral blood flow as determined in wild-type and AQP-4 knockout mice.3 Reduces brain edema when administered after onset of ischemia in rat models.4
Description:
CAS Number: 51987-99-6<br></br>Chemical Name: N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide<br></br>Molecular weight: 206.22<br></br>Formula: C8H6N4OS<br></br>Solubility: DMSO (10 mg/ml with warming) <br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)