bs-82314C
[Life Science]
BTB-1
DATASHEET
Formulation White solid
Storage: RT
Product Information:
A selective, ATP-competitive and reversible inhibitor of mitotic kinesin Kif18A, IC50=1.7 M.1,2 Binds to an allosteric site near Kif18A loop 5 preventing a range of conformational changes thereby blocking motor function.3 Inhibits the differentiation of mouse bone marrow cells to dendritic cells.4 Suppresses the replication of influenza A virus, inhibiting activation of AKT, p38 MAPK, SAPK and RanBP3 leading to the prevention of nuclear export of viral ribonucleoprotein complexes. Greatly improves the viability of IAV-infected mice.5
Description:
CAS Number: 86030-08-2<br></br>Chemical Name: 4-Chloro-2-nitro-1-(phenylsulfonyl)-benzene<br></br>Molecular weight: 297.71<br></br>Formula: C12H8ClNO4S<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.