bs-82312C
[Life Science]
GAC Inhibitor 968
DATASHEET
Formulation Beige solid
Storage: RT
Product Information:
Allosteric inhibitor of glutaminase C (GAC).1 Inhibition of GAC blocks oncogenic transformation induced by Rho GTPases in fibroblasts and B lymphoma cells with no effect on normal cells.2 Inhibits liver-type glutaminase GLS2 and suppresses breast tumor growth in vivo.3,4 Reverses acquired erlotinib resistance in non-small cell lung cancer.5
Description:
CAS Number: 311795-38-7<br></br>Chemical Name: 5-(3-bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]-phenanthridin-4(1H)-<br></br>Molecular weight: 475.42<br></br>Formula: C27H27BrN2O<br></br>Solubility: DMSO (11 mg/ml) Ethanol (1 mg/ml) <br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.