bs-82307C
[Life Science]
NSC33994
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
A remarkably potent and selective JAK2 inhibitor (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM1. Suppresses JAK2-V617F-mediated human pathological cell growth in vitro and in vivo2 and is concomitant with the disruption of intracellular vimentin filaments3. Reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo4.
Description:
CAS Number: 82058-16-0<br></br>Chemical Name: E-4,4’-(1,2-Diethyl-1,2-ethenediyl)bis[2-[(diethylamino)methyl]phenol<br></br>Molecular weight: 436.65<br></br>Formula: C28H42N2O2<br></br>Solubility: DMSO (2 mg/ml) Ethanol (4 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.