DATASHEET
Formulation
Beige solid
Storage:
-20°C
Product Information:
A nonpeptide neurotrophic factor receptor p75 (p75NTR) agonist which promotes survival signaling in neurotrophin-responsive cells.1 Promotes functional recovery in a mouse model of spinal contusion injury.2 Protects neurogenesis after traumatic brain injury.3 Reverses cholinergic neurite dystrophy in Alzheimer’s disease mouse models.4 Stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV-associated neuropathogenesis.5 Orally active and blood-brain barrier permeant.
Description:
CAS Number: 1243259-19-9<br></br>Chemical Name: (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide, dihydrochloride<br></br>Molecular weight: 316.27<br></br>Formula: C12H25N3O2 2HCl<br></br>Solubility: DMSO (20 mg/ml) Ethanol (30 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: 98% by TLC NMR (Conforms)