bs-82303C
[Life Science]
MitoBloCK-12
DATASHEET
Formulation Beige solid
Storage: RT
Product Information:
Attenuates mitochondrial protein import (4-10 M). Discovered in a screen of FDA-approved drugs. Blocks translocation of a mutant form of alanine: glyoxylate aminotransferase (AGT) to the mitochondria and restores AGT trafficking to peroxisomes.1 Also reduces oxalate accumulation and thus has potential to treat patients with primary hyperoxaluria 1 who possess mutations in AGT.1 Also displays antimicrobial activity2, inhibits apamin-sensitive K+ channels3 and induces apoptosis by inhibiting XIAP4.
Description:
CAS Number: 522-51-0<br></br>Chemical Name: 1,1’-Decamethylenebis(4-aminoquinaldinium)dichloride<br></br>Molecular weight: 527.58<br></br>Formula: C30H40Cl2N4<br></br>Solubility: DMSO (1 mg/ml) Water (1 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: >98% by TLC NMR (Conforms)
Size: 50 mg, 250 mg50 mg, 250 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.