bs-82298C
[Life Science]
Fascaplysin
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 μM) and is less selective for Cdk6/D1 (IC50 = 3.4 μM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.
Description:
CAS Number: 114719-57-2<br></br>Chemical Name: 12,13-Dihydro-13-oxopyrido[1,2-a:3,4-b’]diindol-5-ium chloride<br></br>Molecular weight: 306.75<br></br>Formula: C18H11ClN2O4 <br></br>Solubility: DMSO (20 mg/ml) water (2 mg/ml)<br></br>Physical Properties: Dark red-brown solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 1 mg, 5 mg 5 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.