bs-82296C
[Life Science]
PD-150606
DATASHEET
Formulation Yellow solid
Storage: -20°C
Product Information:
A selective, cell-permeable non-peptide calpain inhibitor (Ki for μ- and m-calpains = 0.21 and 0.37 μM respectively). Acts at the calcium binding site of calpain rather than the substrate-binding site. Inhibits calpain activity in two intact cell systems. Attenuates hypoxic/hypoglycemic injury to cerebrocortical neurons in culture and excitotoxic injury to Purkinje cells in cerebellar slices1. Displays cytoprotective effects in oxidant- and calcium ionophore-induced cell death2. Some protective effects may be due to inhibition of MMP activity3.
Description:
CAS Number: 179528-45-1<br></br>Chemical Name: (Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid<br></br>Molecular weight: 306.12<br></br>Formula: C9H7IO2S <br></br>Solubility: DMSO (30 mg/ml) Ethanol (15 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.