DATASHEET
Formulation
Tan solid
Storage:
-20°C
Product Information:
JNK3 inhibitor (Kd = 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively). Displays anti-inflammatory and immunosuppresive activity. Inhibits LPS-induced proinflammatory cytokine and nitric oxide release in vitro.1 Attenuates collagen-induced arthritis severity and inhibits murine delayed-type hypersensitivity in vivo.2
Description:
CAS Number: 1421610-21-0<br></br>Chemical Name: 11H-Indeno[1,2-b]quinoxaline-11-one oxime, sodium salt<br></br>Molecular weight: 269.23<br></br>Formula: C15H8N3O ∙ Na<br></br>Solubility: DMSO (15 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by TLC NMR (Conforms)