bs-82292C
[Life Science]
STF-083010
DATASHEET
Formulation White solid
Storage: RT
Product Information:
A novel small molecule inhibitor of IRE1. It inhibits IRE1 endonuclease activity but not its kinase activity after endoplasmic reticulum stress1-3. It displays significant antimyeloma activity in model human MM xenografts1. Induces apoptosis in pancreatic cancer cells and displays growth inhibition in a clonogenic growth assay in soft agar as well as in a xenograft in vivo model of pancreatic cancer4. Active in vivo.
Description:
CAS Number: 307543-71-1<br></br>Chemical Name: N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide<br></br>Molecular weight: 317.39<br></br>Formula: C15H11NO3S2<br></br>Solubility: DMSO (30 mg/ml)<br></br>Physical Properties: yellow solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.