bs-82286C
[Life Science]
SRPIN340
DATASHEET
Formulation Brown solid
Storage: -20°C
Product Information:
Selective serine arginine protein kinase (SRPK) 1 inhibitor (Ki = 0.89 μM).1 Inhibits SRPK2 at higher concentrations. Does not significantly inhibit other SRPKs such as CLK1 and CLK4, or other classes of SR kinases. Inhibits viral replication by inhibition of host SR protein kinases.1 Modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy2 and controls VEGF-mediated tumor angiogenesis in xenografts3.
Description:
CAS Number: 218156-96-8<br></br>Chemical Name: N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide<br></br>Molecular weight: 349.35<br></br>Formula: C18H18F3N3O<br></br>Solubility: DMSO (40 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by HPLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.