DATASHEET
Formulation
Beige solid
Storage:
-20°C
Product Information:
CARP-1 functional mimetic. Interferes with CARP-1 binding to APC-2 (IC50=10-15 μM)1. Enhances CARP-1 expression and induces G2/M cell cycle arrest. Induces apoptosis and suppresses growth of medulloblastoma cells2 and malignant pleural mesothelioma cells3.
Description:
CAS Number: 331458-02-7<br></br>Chemical Name: 1-[(2-Chlorophenyl)methyl]-5'-phenyl-spiro[3H-indole-3,2'(3'H)-[1,3,4]thiadiazol]-2(1H)-one<br></br>Molecular weight: 405.90<br></br>Formula: C22H16ClN3OS<br></br>Solubility: DMSO (>25 mg/ml)<br></br>Physical Properties: Tan solid<br></br>Purity: 98% by TLC NMR (Conforms)