bs-82281C
[Life Science]
LY-364947
DATASHEET
Formulation White or slightly yellow solid
Storage: RT
Product Information:
Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-β RI, TGF-β RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-β as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.
Description:
CAS Number: 396129-53-6<br></br>Chemical Name: 4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinolone<br></br>Molecular weight: 272.31<br></br>Formula: C17H12N4<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: 98% by TLC
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.