bs-82279C
[Life Science]
Indirubin-3'-monoxime
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
A potent GSK-3β inhibitor (IC50=22 nM)1. Also inhibits CDK1 (IC50=180 nM) and CDK5 (IC50=100 nM)1. Displays antimitotic properties and induces endoreplication following prophase arrest in HBL-100 cells2. Possesses antiangiogenic activity3. Attenuates β-amyloid-associated neuropathology in a mouse model of Alzheimer’s disease4. Cell permeable.
Description:
CAS Number: 160807-49-8<br></br>Chemical Name: 3-[1,3-Dihydro-3-(hydroxyimino-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one<br></br>Molecular weight: 277.29<br></br>Formula: C16H11N3O2 <br></br>Solubility: DMSO (6 mg/ml) Ethanol (4 mg/ml)<br></br>Physical Properties: Dark red or brown solid<br></br>Purity: 98% by TLC, NMR (conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.