bs-82265C
[Life Science]
ABT-418 HCl
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Agonist at neuronal nicotinic acetylcholine receptors displaying the highest potency at α4β2 and α2β2 subtypes (EC50= approximately 6 and 11 μM, respectively).1 Displays anxiolytic activity in a rat model and was 6-fold more potent than diazepam.2 Reduces distractibility in a primate model3 and may have relevance in attention deficit hyperactivity disorder4. Improves cognition in Alzheimer’s disease patients.5
Description:
CAS Number: 147388-83-8<br></br>Chemical Name: 3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole hydrochloride<br></br>Molecular weight: 202.68<br></br>Formula: C9H14N2O HCl <br></br>Solubility: Water (15 mg/ml)<br></br>Physical Properties: Tan solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.