DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Akt activator. Binds to the pleckstrin homology domain of Akt preventing membrane translocation but paradoxically activating it in the cytosol. Enhances Akt phosphorylation by upstream protein kinases. Suppresses excitotoxicity-induced neuronal death in vitro and in vivo.1 A useful tool for studying the PI3K/Akt axis.2
Description:
CAS Number: 305834-79-1<br></br>Chemical Name: 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester<br></br>Molecular weight: 364.79<br></br>Formula: C17H17ClN2O5<br></br>Solubility: DMSO (100 mg/ml) Ethanol (40 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)