bs-82253C
[Life Science]
HTS01037
DATASHEET
Formulation Yellow solid
Storage: RT
Product Information:
Inhibits fatty acid binding proteins. Inhibits lipolysis in 3T3-L1 adipocytes and reduces LPS-stimulated inflammation in cultured macrophages. Acts as an antagonist of the protein-protein interaction between AFABP/aP2 and hormone sensitive lipase but does not activate PPARγ in macrophages1. Inhibits FABP-dependent and fatty acid-stimulated leukotriene C4 biosynthesis2. Reduces intracellular free fatty acid levels, lowering macrophage inflammation and ER stress3. Reduces LPS-stimulated IL-1β secretion in a mouse model4. Inhibits VLDL-induced foam cell formation5.
Description:
CAS Number: 682741-29-3<br></br>Chemical Name: 4-[(3-Carboxy-1-oxo-2-propen-1-yl)amino]-[2,2’-bithiophene]-5-carboxylic acid, 5-methyl ester<br></br>Molecular weight: 337.37<br></br>Formula: C14H11NO5S2<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by HPLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.