DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Inhibits p90 ribosomal S6 kinase (RSK), IC50 = 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively1. Induces a beta-cell-like state in pancreatic apha-cells and induces insulin expression1,2. Increases the endocrine cell content and function of donor human pancreatic islets in culture1. Blocks muscarinic acetylcholine receptor-stimulated RSK activation and subsequent proliferation of SNU-407 colon cancer cells3.
Description:
CAS Number: 376382-11-5<br></br>Chemical Name: 1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinolone-2,7-dione<br></br>Molecular weight: 366.42<br></br>Formula: C24H18N2O2<br></br>Solubility: DMSO (35 mg/ml)<br></br>Physical Properties: Brown solid<br></br>Purity: 98% by TLC, NMR (Conforms)