DATASHEET
Formulation
Yellow solid
Storage:
RT
Product Information:
A potent and selective inhibitor of phosphodiesterase PDE11 (IC50=0.28 μM).1 IC50s for PDE1-10 are greater than 100 μM. Restores the ability of p54nrb / NONOKD cells to generate cAMP in response to ACTH stimulation and the production of cortisol and DHEA in response to cAMP signaling.2
Description:
CAS Number: 686770-80-9<br></br>Chemical Name: 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one<br></br>Molecular weight: 304.44<br></br>Formula: C15H16N2OS2 <br></br>Solubility: DMSO (50 mg/ml) Ethanol (14 mg/ml with warming)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)