DATASHEET
Formulation
Tan solid
Storage:
RT
Product Information:
A selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 μM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50>100 μM1.
Description:
CAS Number: 1596-84-5<br></br>Chemical Name: 1-(2,2-Dimethylhydrazide)butanedioic acid<br></br>Molecular weight: 160.17<br></br>Formula: C6H12N2O3<br></br>Solubility: DMSO (50 mg/ml), water (20 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)