bs-82220C
[Life Science]
LYS6K2
DATASHEET
Formulation Yellow waxy solid
Storage: RT
Product Information:
A selective inhibitor of the p70 ribosomal S6 kinase (S6K)1. Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 μM with no activity at GSK3β and Erk1/2 at 10 μM2. Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K2. Cell permeable.
Description:
CAS Number: 1082949-67-4<br></br>Chemical Name: 4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine<br></br>Molecular weight: 445.42<br></br>Formula: C21H19F4N7<br></br>Solubility: DMSO (1 mg/ml) DMF (3 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 97% by HPLC, NMR (conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.