DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Novel Hedgehog signaling pathway inhibitor (IC50=100-200 nM). Selectively binds to Smo but not other GPCRs. Blocks the formation of and induces the regression of basaloid lesions in skin punches and shrinks UV-induced basaloid lesions in adult mouse skin. Cell permeable.
Description:
CAS Number: 334998-36-6<br></br>Chemical Name: N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide<br></br>Molecular weight: 550.71<br></br>Formula: C31H42N4O5 <br></br>Solubility: DMSO (40 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: Tan solid<br></br>Purity: 98% by TLC, NMR (Conforms)