DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
A pan-specific ubiquitin isopeptidase inhibitor. (IC50= 45, 37 and 9.8 μM for USP2, USP7 and SENP2 respectively) Does not effect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway1,2. Cell permeable.
Description:
CAS Number: 157654-67-6<br></br>Chemical Name: 3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride<br></br>Molecular weight: 339.86<br></br>Formula: C21H21NO · HCl<br></br>Solubility: DMSO (8 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by HPLC, NMR (conforms)