bs-82198C
[Life Science]
SMI-4a
DATASHEET
Formulation Tan solid
Storage: -20°C
Product Information:
A selective, ATP-competitive inhibitor of the Pim protein kinases (IC50 = 24 and 100 nM for Pim-1 and Pim-2 respectively). Selective over a panel of ~50 other kinases1. Induces cell cycle arrest in leukemia and prostate cancer cells2. Blocks the growth of a wide range of myeloid and lymphoid cell lines with precursor T-cell lymphoblastic leukemia/lymphoma (pre-T-LBL/T-ALL) being highly sensitive3. A useful tool for exploring the involvement of Pim in cellular signaling4. Cell permeable.
Description:
CAS Number: 438190-29-5<br></br>Chemical Name: 5-(3-Trifluoromethylbenzylidene)thiazolidine<br></br>Molecular weight: 273.23<br></br>Formula: C11H6F3NO2S<br></br>Solubility: DMSO (100 mg/ml) Ethanol (40 mg/ml)<br></br>Physical Properties: Tan solid<br></br>Purity: 98% by TLC, NMR (conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.