bs-82194C
[Life Science]
Wiskostatin
DATASHEET
Formulation Red solid
Storage: RT
Product Information:
A selective, reversible inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity1. Binds to the regulatory domain of N-WASP and inhibits activation of Arp2/3 complex by forcing N-WASP into an inactive conformation2. Inhibits PIP2-induced actin polymerization (EC50=4 μM). Perturbs agrin-elicited acetylcholine receptor clustering3. Inhibits the formation of dendritic spines and synapses in hippocampal neurons4.
Description:
CAS Number: 253449-04-6<br></br>Chemical Name: 1-(3,6-Dibromocarbazol-9-yl)-3-dimethylaminopropan-2-ol<br></br>Molecular weight: 426.15<br></br>Formula: C17H18Br2N2O<br></br>Solubility: DMSO (30 mg/ml) Ethanol (10 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC [9:1 CH2Cl2/CH3OH Rf = 0.16] NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.