DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Abrogates the deubiquitinating activity of the 19S regulatory particle by inhibiting ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) resulting in accumulation of polyubiquitin in cells. b-AP15 induces tumor cell apoptosis and tumor progression in four different solid tumor models in vivo.
Description:
CAS Number: 1009817-63-3<br></br>Chemical Name: 3,5-bis[(4-Nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one<br></br>Molecular weight: 419.40<br></br>Formula: C22H17N3O6<br></br>Solubility: DMSO (35 mg/ml)<br></br>Physical Properties: Pale yellow solid. (MP = 170-174°C)<br></br>Purity: >98% by HPLC