DATASHEET
Formulation
White solid
Storage:
-20°C
Product Information:
Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7µM and PCAF IC50=5µM) both in vitro and in vivo.1 It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.2
Description:
CAS Number: 78824-30-3<br></br>Chemical Name: <br></br>Molecular weight: 602.80<br></br>Formula: C38H50O6<br></br>Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: >95%