A novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. Binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.
Description:
CAS Number: 6964-62-1<br></br>Chemical Name: 2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol<br></br>Molecular weight: 340.43<br></br>Formula: C23H20N2O<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 97% by TLC / HPLC NMR (Conforms)
Size:
10 mg, 50 mg10 mg, 50 mg
Applications:Life Science()
For research use only. Not intended for diagnostic or therapeutic use.