DATASHEET
Formulation
Light yellow solid
Storage:
-20°C
Product Information:
Suppresses Wnt/β-catenin signaling. It antagonizes PPARγ and PPARδ ligand-dependent activation which is mediated by inhibition of recruitment of the coactivators β-catenin and GRIP1 but not the corepressors NCoR and SMRT1. Inhibits the migration and growth of breast cancer cell lines2 as well as colon, lung and liver cell lines1. Useful tool for probing the involvement of Wnt signaling pathway3,4.
Description:
CAS Number: 108409-83-2<br></br>Chemical Name: 2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide<br></br>Molecular weight: 361.21<br></br>Formula: C13H10Cl2N2O4S<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Tan solid<br></br>Purity: 98% by TLC, NMR (Conforms)