bs-82179C
[Life Science]
A83-01
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
Potent and selective ALK4, 5 and 7 inhibitor1,2. IC50=45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFβ2. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency3. Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts4. Cell permeable. Active in vivo.
Description:
CAS Number: 909910-43-6<br></br>Chemical Name: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide<br></br>Molecular weight: 421.53<br></br>Formula: C25H19N5S<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Light yellow solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.