DATASHEET
Formulation
Off-white solid
Storage:
-20°C
Product Information:
Inhibits ubiquitin C-terminal hydrolase (UCH-L1) (Ki=0.4 M). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. Cell permeable.
Description:
CAS Number: 668467-91-2<br></br>Chemical Name: 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)<br></br>Molecular weight: 397.65<br></br>Formula: C17H11Cl3N2O3<br></br>Solubility: DMSO (20 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by TLC, NMR conforms