DATASHEET
Formulation
Pale yellow solid
Storage:
-20°C
Product Information:
An analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity.1,2 After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes.3 Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.4
Description:
CAS Number: 70-00-8<br></br>Chemical Name: 2’-Deoxy-5-trifluoromethyluridine<br></br>Molecular weight: 296.20<br></br>Formula: C10H11F3N2O5 <br></br>Solubility: DMSO (25 mg/ml) Water (14 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by HPLC, NMR (Conforms)