bs-82148C
[Life Science]
Cytarabine
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
A nucleoside analog that interferes with DNA synthesis and transcription, particularly in tumor cells.1,2 It Cellular enzymes convert it to its nucleotide form, Ara-CTP, which disrupts DNA and RNA synthesis when polymerases attempt to incorporate it.3,4 For the same reasons, it is also employed as an antiviral.5 It inhibits proliferation of a variety of leukemic cell lines (IC50s 16-72 nM), but is used primarily against acute myeloid leukemia (AML).6,7
Description:
CAS Number: 147-94-4<br></br>Chemical Name: 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone<br></br>Molecular weight: 243.22<br></br>Formula: C9H13N3O5<br></br>Solubility: DMSO (12 mg/ml) Water (24 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by HPLC NMR (Conforms)
Size: 500 mg, 2 g500 mg, 2 g
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.