bs-82136C
[Life Science]
2-APB
DATASHEET
Formulation White solid
Storage: -20°C
Product Information:
An IP3 receptor antagonist (IC50=42 μM).1 Inhibits store-operated Ca2+ channels at high concentrations (50 μM) but stimulates at low concs. (<10 μM).2 Modulates TRP channels, blocking TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8, TRPP2 and at higher concentrations, activating TRPV1, TRPV2, TRPV3.3,4 Also inhibits selected GAP junction subtypes.5
Description:
CAS Number: 524-95-8<br></br>Chemical Name: 2-Aminoethoxydiphenyl borate<br></br>Molecular weight: 225.1<br></br>Formula: C14H16BNO<br></br>Solubility: DMSO (20 mg/ml) Ethanol (5 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR Conforms
Size: 100 mg, 250 mg100 mg, 250 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.