bs-82129C
[Life Science]
GSK-1016790A
DATASHEET
Formulation Beige solid
Storage: -20°C
Product Information:
A novel and potent TRPV4 channel agonist. GSK1016790A induced Ca2+ influx in mouse and human TRPV4 expressing HEK cells (EC50 values of 18 and 2.1 nM, respectively), and evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM. It is 300-fold more potent than 4α-PDD and is a valuable tool for investigating the role of TRPV4 in physiological processes.
Description:
CAS Number: 942206-85-1<br></br>Chemical Name: (N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide<br></br>Molecular weight: 655.62<br></br>Formula: C28H32Cl2N4O6S2<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: white solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.