DATASHEET
Formulation
White solid (MP = 77-78°C)
Storage:
-20°C
Product Information:
An extremely potent uncoupler of mitochondrial oxidative phosphorylation (IC50 = 20 nM).1 Induces apoptosis in a variety of cell lines.2 Inhibits wild type and mutant beta-amyloid production in embryonic kidney 293 cells expressing either wild-type or “Swedish” mutant APP.3 An important tool for inhibiting mitochondrial membrane potential.2,4 Cell permeable.
Description:
CAS Number: 370-86-5<br></br>Chemical Name: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone<br></br>Molecular weight: 254.17<br></br>Formula: C10H5F3N4O<br></br>Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: Pale yellow solid<br></br>Purity: 98% by TLC [10% ethyl acetate in hexanes; Rf = 0.38] NMR Conforms