bs-82098C
[Life Science]
P7C3
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
P7C3 exerts proneurogenic activity by protecting newborn neurons from apoptosis. Prolonged administration to aged rats impedes neuronal death and preserves cognitive capacity.1 Delays disease progression in G93A-SOD2 mutant mouse model of amyotrophic lateral sclerosis.2 Blocks MPTP-mediated cell death of dopaminergic neurons in the substantia nigra of adult mice, a model of Parkinson disease.3 Restores hippocampal neurogenesis in a mouse model of Down Syndrome.4 The mechanism of action involves activation of nicotinamide phosphoribosyltransferase (NAMPT) with concomitant increase of intracellular levels of NAD.5 Active in vivo.
Description:
CAS Number: 301353-96-8<br></br>Chemical Name: 1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol<br></br>Molecular weight: 474.20<br></br>Formula: C21H18Br2N2O<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.