DATASHEET
Formulation
Yellow solid
Storage:
-20°C
Product Information:
All−trans−Retinoic acid (ATRA; a metabolite of Vitamin A) is an endogenous ligand for the retinoic acid receptor (RAR). The binding of retinoic acid to the RAR and retinoid X (RXR) heterodimer causes conformation changes in RAR that affects the binding of other proteins that regulate the growth and differentiation of a variety of both normal and malignant cells.1 ATRA promotes differentiation of embryonic stem cells (ESCs) into a variety of cell types in vitro.2-4
Description:
CAS Number: 302-79-4<br></br>Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid<br></br>Molecular weight: 300.44<br></br>Formula: C20H28O2<br></br>Solubility: DMSO (8 mg/ml) Ethanol (15 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% NMR Conforms