bs-82082C
[Life Science]
AP-18
DATASHEET
Formulation White solid
Storage: RT
Product Information:
TRPA1 channel blocker IC50=3.1-4.5 μM in various cell lines. Reduces cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. Does not block TRPV1, V2, V3, V4 or M8 at concentrations up to 50 μM.1 Blocks TRPA1 pore dilation (IC50=10.3 μM).2 An important tool for assessing the role of TRPA1 in cell signaling and physiological processes.3-5
Description:
CAS Number: 55224-94-7<br></br>Chemical Name: 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime<br></br>Molecular weight: 209.67<br></br>Formula: C11H12ClNO<br></br>Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC [10% Methanol in methylene chloride, Rf = 0.60] NMR Conforms
Size: 10 mg, 50 mg10 mg, 50 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.