bs-82080C
[Life Science]
Sulindac Sulfone
DATASHEET
Formulation Yellow solid
Storage: RT
Product Information:
Metabolite of the cyclooxygenase inhibitor sulindac that induces apoptosis via inhibition of type 5 phosphodiesterases.1 Sulindac sulfone does not inhibit cyclooxygenase at physiological concentrations but does inhibit K-ras-dependent cyclooxygenase-2 expression in colon cancer cells.2
Description:
CAS Number: 59864-04-9<br></br>Chemical Name: (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid<br></br>Molecular weight: 372.41<br></br>Formula: C20H17FO4S<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: >98% by TLC [10% methanol / methylene chloride, Rf = 0.40] NMR (Conforms)
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.