DATASHEET
Formulation
Yellow solid (MP = 223-224°C)
Storage:
-20°C
Product Information:
Inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 µM). No inhibition of EGF, or PDGF receptor phosphorylation at typical working concentrations.
Description:
CAS Number: 148741-30-4<br></br>Chemical Name: 3,5-Di-t-butyl-4-hydroxybenzylidene cyanothioacetamide<br></br>Molecular weight: 316.47<br></br>Formula: C18H24N2OS<br></br>Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: Yellow solid (MP = 223-224°C)<br></br>Purity: 99% by TLC [5% methanol in methylene chloride, Rf = 0.76] NMR Conforms