DATASHEET
Formulation
Off-white solid
Storage:
RT
Product Information:
NAD(P)H oxidase (Nox) inhibitor. Abolishes PDGF-mediated Nox activation and ROS production (100% at 10 M). Inhibits PMA-induced oxidative burst in HL-60 cells (IC50=2 µM). Enhances TGF-ß-induced apoptosis in liver tumor cells.
Description:
CAS Number: 722456-31-7<br></br>Chemical Name: 3-Benyl-7-(2-benzoxazolyl)yhio-1,2,3-triazolo(4,5-d)pyrimidine<br></br>Molecular weight: 360.4<br></br>Formula: C18H12N6OS<br></br>Solubility: DMSO (10 mg/ml) DMF (25 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC, NMR conforms