DATASHEET
Formulation
white solid (MP = 128-130°C)
Storage:
RT
Product Information:
Potent, selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8. Nav1.8 is preferentially expressed in sensory neurons, and inhibition attenuates both inflammatory and neuropathic pain in a variety of animal models. IC50's for rat and human Nav1.8 are 140 nM and 8.0 nM respectively.
Description:
CAS Number: 944261-79-4<br></br>Chemical Name: 5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide<br></br>Molecular weight: 357.80<br></br>Formula: C19H16ClNO4<br></br>Solubility: DMSO (15 mg/ml) Ethanol (2 mg/ml)<br></br>Physical Properties: white solid (MP = 128-130°C)<br></br>Purity: 98% by TLC [50% ethyl acetate in hexanes, Rf = 0.58] NMR Conforms