bs-82026C
[Life Science]
MK-886
DATASHEET
Formulation White solid
Storage: RT
Product Information:
Inhibitor of leukotriene biosynthesis(IC50 = 2.5 nM in human PMN)1 via 5-lipoxygenase-activating protein (FLAP) inhibition (IC50 = 30 nM)2. Also inhibits PPARα (80% inhibition at 10 µM).3
Description:
CAS Number: 118414-82-7<br></br>Chemical Name: 3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid<br></br>Molecular weight: 472.08<br></br>Formula: C27H34ClNO2S<br></br>Solubility: DMSO (40 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC [ 5% methanol in methylene chloride; Rf = 0.35] NMR conforms
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.