DATASHEET
Formulation
Yellow solid
Storage:
RT
Product Information:
Potent (EC50 = 1.3nM) and selective Leukotriene D4 antagonist(LTD4)1 displaying inverse agonist activity2, Blocks binding of LTD4 to human (Ki = 0.22 nM) and guinea pig (Ki = 2.1 nM) lung membranes. Selective for the CysLT1 receptor. Multidrug resistance protein 1 (MRP1) inhibitor.3
Description:
CAS Number: 115104-28-4<br></br>Chemical Name: 5-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid<br></br>Molecular weight: 515.09<br></br>Formula: C26H27ClN2O3S2<br></br>Solubility: DMSO (50 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 95% by TLC [10% methanol in methylene chloride; Rf = 0.34] NMR conforms