bs-82023C
[Life Science]
STO-609
DATASHEET
Formulation Yellow solid
Storage: RT
Product Information:
Selective inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki = 80 and 15 ng/ml for inhibition of CaM-KKα and CaM-KKβ respectively).1 Binds to the ATP-binding site.2 Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. Important tool for probing distinct CaMK pathways in LTP.3 Reduces starvation-induced autophagosomal membrane formation.4 Reverses age-associated decline in bone mass.5 Stimulates osteoblast formation, inhibits osteoclast differentiation.6
Description:
CAS Number: 52029-86-4<br></br>Chemical Name: 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate<br></br>Molecular weight: 314.30 ∙ 60.05<br></br>Formula: C19H10N2O3 ∙ CH3COOH<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 98% by TLC NMR conforms
Size: 5 mg, 25 mg5 mg, 25 mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.